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If additional glycaemic control is needed after at least 4 weeks, the dose may be increased to 1 mg once weekly and potentially to 2 mg once weekly if required and tolerated

The funders have no role in the study design, in data collection, analysis and interpretation, in writing the report, and in the decision to submit the article for publication

No dose adjustment is recommended at this time [10]

The generation of ROS as by-products of the mitochondrial electron transport chain (ETC) involves superoxide radicals and hydrogen peroxide (Jomova et al

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Citrate, generated by reductive carboxylation of -KG, is especially crucial for lipid synthesis under low-oxygen conditions 24,25